1-Bromopropane

1-Bromopropane

Hazard Overview

Hazard Overview

What is 1-bromopropane?

1-Bromopropane, also known as n-propyl bromide, is an example of a class of chemical compounds known as alkyl bromides. 1-Bromopropane is used in the United States as a solvent in industrial and commercial applications and has been substituted for other solvents that have been identified as suspect human carcinogens or ozone-depleting chemicals. Among its uses, 1-bromopropane has been used as a solvent for spray adhesives, vapor degreasing, and as a substitute for perchloroethylene in dry cleaning.

How can I be exposed to 1-bromopropane?

Occupational exposure to 1-bromopropane can occur by inhalation and skin contact, although exposure through ingestion and the eyes have been observed to be other possible exposure routes.

What are the health hazards of 1-bromopropane?

Short-term exposure to the chemical can result in irritation of the eyes, nose, throat or respiratory tract. Chronic (long-term) exposure to 1-bromopropane can adversely affect peripheral nerves and the central nervous system. Symptoms that have been reported include joint pain or leg weakness and pain leading to difficulty standing and walking; muscle twitching or numbness, tingling and prickling in the hands or feet, loss of vibration sense, anxiety, apathy, insomnia, and difficulties with concentration and memory.

Other health effects that may also occur include dermatitis, nausea and vomiting, diarrhea, difficulty in swallowing, disruption or failure of menstruation, urinary difficulties, anemia or low hematocrit (red blood cell count), liver damage, and lung disease.

What are the physical hazards of 1-bromopropane?

1-Bromopropane is classified as a Category 2 flammable liquid. It has an autoignition temperature of 914 degrees F and a flash point of less than 72 degrees F. Although a specific upper explosive (flammability) limit has not been determined, it has a lower explosive limit of 4.6 percent by volume in air. 1-Bromopropane decomposes when burned to emit hydrogen bromide (HBr) gas.

Solutions

Solutions

What can I do to protect myself?

Your employer must provide the appropriate personal protective equipment when work practices and existing engineering controls cannot prevent contact with 1-bromopropane through the skin and eyes or by inhalation.

What resources are available to assist employers?

Other related resources can be found on the A-Z safety and health topics pages for respiratory protection, hazard communication, eyewash stations and emergency showers and personal protective equipment. In addition, the NCDOL Library offers free safety and health videos and related research assistance on consensus standards (i.e., ANSI, NFPA, NEC). The education, training and technical assistance bureau provides free online safety and health training and outreach services (i.e., speaker's bureau requests, safety booths) upon request.

 

Regulations

Regulations

Which standards apply?

There are no substance specific occupational safety and health standards that apply to 1-bromopropane. Where workers are overexposed above the ACGIH Threshold Limit Value (TLV) of 0.1 parts per million (ppm) as an 8 hour time-weighted average (TWA), the General Duty Clause (NCGS 95-129(1)) of the  Occupational Safety and Health Act of North Carolina can be invoked.

Other related standards that may apply include:

Learn More

Learn More

Where can I learn more?

If you would like to receive interpretive guidance on this or any other OSH standard or topic, you can submit your questions using the Ask OSH web form, by e-mail to ask.osh@labor.nc.gov or by calling 919-707-7876.